ISPD - Isoprenoid synthase domain-containing protein - human protein (Function)
 
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ISPD »  Isoprenoid synthase domain-containing protein   [ EC 2.7.7.- ]
 
Protein also known as:  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein.
Gene name:  ISPD
Family name: IspD
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 18 2
GENE REF ISO

Function

 show evidences
Overview 
Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in synthesis of a nucleotide sugar. Required for dystroglycan O-mannosylation.  
3
  • UniProtKB
GO molecular function 
Nucleotidyltransferase activitydefinition[GO:0016779]  
1
  • UniProtKB KW
GO biological process 
Axon guidancedefinition[GO:0007411] silver  
1
  • Ortholog Compara
Isoprenoid biosynthetic processdefinition[GO:0008299] silver  
1
  • InterPro 2 GO
Protein O-linked mannosylationdefinition[GO:0035269]  
2
  • UniProtKB
Pathways 
This protein is involved in the following pathway
Protein modification; protein glycosylation  
1
  • UniProtKB
 

Keywords

Molecular function 
Nucleotidyltransferase  definition   [KW-0548]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 729920
PRO: PR:A4D126