GMNC - Geminin coiled-coil domain-containing protein 1 - human protein (Function)
 
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Protein
Gene
References

 
GMNC »  Geminin coiled-coil domain-containing protein 1
 
Gene name:  GMNC
Family name: GEMC1
Entry whose protein(s) existence is based on homology
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GENE REF ISO

Function

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Overview 
Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity).  
1
  • UniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682]  
1
  • Ortholog Curator
GO biological process 
Cell cycledefinition[GO:0007049]  
1
  • UniProtKB KW
Cell proliferationdefinition[GO:0008283]  
1
  • Ortholog Curator
DNA replication initiationdefinition[GO:0006270] silver  
1
  • InterPro 2 GO
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
DNA replication  definition   [KW-0235]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 647309
PRO: PR:A6NCL1