GMNC - Geminin coiled-coil domain-containing protein 1 - human protein (Function)
 
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Protein
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GMNC »  Geminin coiled-coil domain-containing protein 1
 
Gene name:  GMNC
Family name: GEMC1
Entry whose protein(s) existence is based on homology
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GENE REF ISO

Function

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Overview 
Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682]  
  • ISSOrtholog Curator
GO biological process 
Cell cycledefinition[GO:0007049]  
  • IEAUniProtKB KW
Cell proliferationdefinition[GO:0008283]  
  • ISSOrtholog Curator
DNA replicationdefinition[GO:0006260] silver  
  • IEAOrtholog Compara
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
DNA replication  definition   [KW-0235]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links