DBX1 - Homeobox protein DBX1 - human protein (Function)
 
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Protein
Gene
References

 
DBX1 »  Homeobox protein DBX1
 
Gene name:  DBX1
Family name: H2.0 homeobox
Entry whose protein(s) existence is based on evidence at transcript level
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GENE REF ISO

Function

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Overview 
Could have a role in patterning the central nervous system during embryogenesis. Has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. Regulates the transcription factor profile, neurotransmitter phenotype, intraspinal migratory path and axonal trajectory of V0 neurons, features that differentiate them from an adjacent set of V1 neurons (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
Transcription regulatory region sequence-specific DNA bindingdefinition[GO:0000976] silver  
  • IEAInterPro 2 GO
GO biological process 
Multicellular organismal developmentdefinition[GO:0007275]  
  • IEAUniProtKB KW
Regulation of transcription, DNA-templateddefinition[GO:0006355] silver  
  • IEAInterPro 2 GO
 

Keywords

Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: DBX1
GenomeRNAi: 120237
PRO: PR:A6NMT0