KCNK1 - Potassium channel subfamily K member 1 - human protein (Function)
 
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Protein
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References

 
KCNK1 »  Potassium channel subfamily K member 1
 
Protein also known as:  Inward rectifying potassium channel protein TWIK-1.
Gene name:  KCNK1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 19 1
GENE REF ISO

Function

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Overview 
Weakly inward rectifying potassium channel.  
1
  • CuratedUniProtKB
GO molecular function 
Inward rectifier potassium channel activitydefinition[GO:0005242]  
1
  • TASPINC
GO biological process 
Potassium ion transmembrane transportdefinition[GO:0071805]  
  • IEAUniProtKB KW
Potassium ion transportdefinition[GO:0006813]  
1
  • TASPINC
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • IEAUniProtKB KW
Response to nicotinedefinition[GO:0035094] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)  REACT_75779  
Note 
Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KCNK1
GenomeRNAi: 3775
PRO: PR:O00180