PDHX - Pyruvate dehydrogenase protein X component, mitochondrial - human protein (Function)
 
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Protein
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References

 
PDHX »  Pyruvate dehydrogenase protein X component, mitochondrial
 
Protein also known as:  Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex.
Gene name:  PDHX
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.  
  • CuratedUniProtKB
GO molecular function 
Transferase activity, transferring acyl groupsdefinition[GO:0016746] silver  
  • IEAInterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathway:
Metabolic pathways  hsa01100+8050  
According to Reactome, this protein belongs to the following pathways:
Pyruvate metabolism  REACT_2071  
Regulation of pyruvate dehydrogenase (PDH) complex  REACT_12528  
 
More information is available from:
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: E3_binding_protein
GenomeRNAi: 8050
PRO: PR:O00330