BTN3A1 - Butyrophilin subfamily 3 member A1 - human protein (Function)
 
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BTN3A1 »  Butyrophilin subfamily 3 member A1
 
Protein also known as:  CD antigen CD277.
Gene name:  BTN3A1
Family name: Immunoglobulin » BTN/MOG
Entry whose protein(s) existence is based on evidence at protein level
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1 26 4
GENE REF ISO

Function

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Overview 
Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.  
4
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Activated T cell proliferationdefinition[GO:0050798]  
1
  • IMPUniProtKB
Cytokine secretiondefinition[GO:0050663]  
1
  • IDAUniProtKB
Interferon-gamma secretiondefinition[GO:0072643]  
1
  • IMPUniProtKB
T cell receptor signaling pathwaydefinition[GO:0050852]  
1
  • IDAUniProtKB
 

Keywords

Biological process 
Adaptive immunity  definition   [KW-1064]
Immunity  definition   [KW-0391]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links