BIN1 - Myc box-dependent-interacting protein 1 - human protein (Function)
 
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BIN1 »  Myc box-dependent-interacting protein 1
 
Protein also known as:  Box-dependent myc-interacting protein 1.
Gene name:  BIN1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

 show evidences
Overview 
May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.  
1
  • UniProtKB
GO molecular function 
GTPase bindingdefinition[GO:0051020] silver  
1
  • Ortholog Compara
Identical protein bindingdefinition[GO:0042802]  
1
  • IntAct
Protein bindingdefinition[GO:0005515]  
11
  • IntAct
  • Alzheimers_University_of_Toronto
Protein complex bindingdefinition[GO:0032403] silver  
1
  • Ortholog Compara
Protein heterodimerization activitydefinition[GO:0046982] silver  
1
  • Ortholog Compara
RNA polymerase bindingdefinition[GO:0070063]  
1
  • AgBase
Tau protein bindingdefinition[GO:0048156]  
1
  • Alzheimers_University_of_Toronto
GO biological process 
Cell proliferationdefinition[GO:0008283]  
1
  • PINC
Endocytosisdefinition[GO:0006897]  
1
  • UniProtKB KW
Lipid tube assemblydefinition[GO:0060988]  
1
  • Alzheimers_University_of_Toronto
Muscle cell differentiationdefinition[GO:0042692] silver  
1
  • Ortholog Compara
Positive regulation of apoptotic processdefinition[GO:0043065]  
2
  • AgBase
  • Alzheimers_University_of_Toronto
Positive regulation of astrocyte differentiationdefinition[GO:0048711]  
1
  • Alzheimers_University_of_Toronto
Positive regulation of endocytosisdefinition[GO:0045807] silver  
1
  • Ortholog Compara
Positive regulation of GTPase activitydefinition[GO:0043547] silver  
1
  • Ortholog Compara
Regulation of cell cycle arrestdefinition[GO:0071156]  
1
  • Alzheimers_University_of_Toronto
Regulation of neuron differentiationdefinition[GO:0045664]  
1
  • Alzheimers_University_of_Toronto
Viral processdefinition[GO:0016032]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Endocytosis  definition   [KW-0254]
Host-virus interaction  definition   [KW-0945]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: BIN1
GenomeRNAi: 274
PRO: PR:O00499