BCL9 - B-cell CLL/lymphoma 9 protein - human protein (Function)
 
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Protein
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BCL9 »  B-cell CLL/lymphoma 9 protein  (Bcl-9)
 
Protein also known as:  Protein legless homolog.
Gene name:  BCL9
Family name: BCL9
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 53 1
GENE REF ISO

Function

 show evidences
Overview 
Involved in signal transduction through the Wnt pathway. Promotes beta-catenin's transcriptional activity (By similarity).  
1
  • CuratedUniProtKB
GO molecular function 
Beta-catenin bindingdefinition[GO:0008013] silver  
  • IEAOrtholog Compara
Protein bindingdefinition[GO:0005515]  
5
  • IPIIntAct
GO biological process 
Canonical Wnt signaling pathwaydefinition[GO:0060070] silver  
  • IEAOrtholog Compara
Myotube differentiation involved in skeletal muscle regenerationdefinition[GO:0014908] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Not  Regulation of transforming growth factor beta receptor signaling pathwaydefinition[GO:0017015]  
1
  • IMPBHF-UCL
Skeletal muscle cell differentiationdefinition[GO:0035914] silver  
  • IEAOrtholog Compara
Somatic stem cell maintenancedefinition[GO:0035019] silver  
  • IEAOrtholog Compara
Pathways 
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Biological process 
Wnt signaling pathway  definition   [KW-0879]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: BCL9
GenomeRNAi: 607
PRO: PR:O00512