MPHOSPH10 - U3 small nucleolar ribonucleoprotein protein MPP10 - human protein (Function)
 
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MPHOSPH10 »  U3 small nucleolar ribonucleoprotein protein MPP10
 
Protein also known as:  M phase phosphoprotein 10.
Gene name:  MPHOSPH10
Family name: MPP10
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 29 1
GENE REF ISO

Function

 show evidences
Overview 
Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.  
  • CuratedUniProtKB
GO molecular function 
Poly(A) RNA bindingdefinition[GO:0044822]  
2
  • IDAUniProtKB
Protein bindingdefinition[GO:0005515]  
3
  • IPIIntAct
  • IPIHGNC
GO biological process 
Negative regulation of phosphatase activitydefinition[GO:0010923]  
1
  • IDAUniProtKB
RNA processingdefinition[GO:0006396]  
1
  • NASUniProtKB
RNA splicingdefinition[GO:0008380]  
1
  • NASUniProtKB
RNA splicing, via transesterification reactionsdefinition[GO:0000375]  
1
  • NASUniProtKB
rRNA processingdefinition[GO:0006364]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Ribosome biogenesis in eukaryotes  hsa03008+10199  
 

Keywords

Biological process 
Ribosome biogenesis  definition   [KW-0690]
rRNA processing  definition   [KW-0698]
Molecular function 
Ribonucleoprotein  definition   [KW-0687]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MPHOSPH10
GenomeRNAi: 10199
PRO: PR:O00566