CXCR6 - C-X-C chemokine receptor type 6 - human protein (Function)
 
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Protein
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References

 
CXCR6 »  C-X-C chemokine receptor type 6  (CXCR-6)
 
Protein also known as:  G-protein coupled receptor STRL33; CD antigen CD186.
Gene name:  CXCR6
Entry whose protein(s) existence is based on evidence at transcript level
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1 46 1
GENE REF ISO

Function

 show evidences
Overview 
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.  
  • CuratedUniProtKB
GO molecular function 
C-X-C chemokine receptor activitydefinition[GO:0016494] silver  
  • IEAOrtholog Compara
Coreceptor activitydefinition[GO:0015026] silver  
  • IEAInterPro 2 GO
G-protein coupled receptor activitydefinition[GO:0004930]  
1
  • TASPINC
GO biological process 
Chemotaxisdefinition[GO:0006935] silver  
  • IEAInterPro 2 GO
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Inflammatory responsedefinition[GO:0006954] silver  
  • IEAInterPro 2 GO
Viral genome replicationdefinition[GO:0019079]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Chemokine signaling pathway  hsa04062+10663  
Cytokine-cytokine receptor interaction  hsa04060+10663  
According to Reactome, this protein belongs to the following pathway:
Signal Transduction  REACT_111102  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: CXCR6
GenomeRNAi: 10663
PRO: PR:O00574
Chemistry
GuidetoPHARMACOLOGY: 73