BAI1 - Brain-specific angiogenesis inhibitor 1 - human protein (Function)
 
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Protein
Gene
References

 
BAI1 »  Brain-specific angiogenesis inhibitor 1
 
Gene name:  BAI1
Entry whose protein(s) existence is based on evidence at protein level
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1 27 1
GENE REF ISO

Function

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Overview 
Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain.  
1
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
  • IEAUniProtKB KW
GO biological process 
Axonogenesisdefinition[GO:0007409]  
1
  • TASPINC
Cell adhesiondefinition[GO:0007155]  
  • IEAUniProtKB KW
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASGDB
Negative regulation of angiogenesisdefinition[GO:0016525] silver  
  • IEAInterPro 2 GO
Negative regulation of cell proliferationdefinition[GO:0008285]  
1
  • TASPINC
Neuropeptide signaling pathwaydefinition[GO:0007218] silver  
  • IEAInterPro 2 GO
Peripheral nervous system developmentdefinition[GO:0007422]  
1
  • TASPINC
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
p53 signaling pathway  hsa04115+575  
 

Keywords

Biological process 
Cell adhesion  definition   [KW-0130]
Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: Brain-specific_angiogenesis_inhibitor_1
GenomeRNAi: 575
PRO: PR:O14514
Chemistry
GuidetoPHARMACOLOGY: 174