SDHD - Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial - human protein (Function)
 
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SDHD »  Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial  (CybS)
 
Protein also known as:  Succinate-ubiquinone oxidoreductase cytochrome b small subunit.
Gene name:  SDHD
Family name: CybS
Entry whose protein(s) existence is based on evidence at protein level
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1 82 4
GENE REF ISO

Function

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Overview 
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity).  
  • CuratedUniProtKB
GO molecular function 
Electron carrier activitydefinition[GO:0009055]  
1
  • TASUniProtKB
Heme bindingdefinition[GO:0020037]  
  • ISSOrtholog Curator
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Succinate dehydrogenase activitydefinition[GO:0000104]  
1
  • IDAUniProtKB
Ubiquinone bindingdefinition[GO:0048039]  
  • ISSOrtholog Curator
GO biological process 
Tricarboxylic acid cycledefinition[GO:0006099]  
1
  • IDAUniProtKB
  • IEAUniPathway
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Alzheimer's disease  hsa05010+6392  
Citrate cycle (TCA cycle)  hsa00020+6392  
Huntington's disease  hsa05016+6392  
Metabolic pathways  hsa01100+6392  
Oxidative phosphorylation  hsa00190+6392  
Parkinson's disease  hsa05012+6392  
According to Reactome, this protein belongs to the following pathways:
Citric acid cycle (TCA cycle)  REACT_1785  
Respiratory electron transport  REACT_22393  
 
More information is available from:
 

Keywords

Biological process 
Electron transport  definition   [KW-0249]
Transport  definition   [KW-0813]
Tricarboxylic acid cycle  definition   [KW-0816]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SDHD
GenomeRNAi: 6392
PRO: PR:O14521