SDHD - Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial - human protein (Function)
 
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SDHD »  Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial  (CybS)
 
Protein also known as:  Succinate-ubiquinone oxidoreductase cytochrome b small subunit.
Gene name:  SDHD
Family name: CybS
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).  
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  • UniProtKB
GO molecular function 
Electron carrier activitydefinition[GO:0009055]  
1
  • UniProtKB
Heme bindingdefinition[GO:0020037]  
1
  • Ortholog Curator
Metal ion bindingdefinition[GO:0046872]  
1
  • UniProtKB KW
Succinate dehydrogenase activitydefinition[GO:0000104]  
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  • UniProtKB
Ubiquinone bindingdefinition[GO:0048039]  
1
  • Ortholog Curator
GO biological process 
Cellular response to hypoxiadefinition[GO:0071456] silver  
1
  • Ortholog Compara
Regulation of catecholamine secretiondefinition[GO:0050433] silver  
1
  • Ortholog Compara
Tricarboxylic acid cycledefinition[GO:0006099]  
2
  • UniProtKB
  • UniPathway
Pathways 
This protein is involved in the following pathway
Carbohydrate metabolism; tricarboxylic acid cycle  
1
  • UniProtKB
According to KEGG, this protein belongs to the following pathways:
Alzheimer's disease  hsa05010+6392  
Citrate cycle (TCA cycle)  hsa00020+6392  
Huntington's disease  hsa05016+6392  
Metabolic pathways  hsa01100+6392  
Oxidative phosphorylation  hsa00190+6392  
Parkinson's disease  hsa05012+6392  
According to Reactome, this protein belongs to the following pathways:
Citric acid cycle (TCA cycle)  REACT_1785  
Respiratory electron transport  REACT_22393  
 
More information is available from:
 

Keywords

Biological process 
Electron transport  definition   [KW-0249]
Transport  definition   [KW-0813]
Tricarboxylic acid cycle  definition   [KW-0816]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: SDHD
GenomeRNAi: 6392
PRO: PR:O14521