EI24 - Etoposide-induced protein 2.4 homolog - human protein (Function)
 
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Protein
Gene
References

 
EI24 »  Etoposide-induced protein 2.4 homolog
 
Protein also known as:  p53-induced gene 8 protein.
Gene name:  EI24
Family name: EI24
Entry whose protein(s) existence is based on evidence at protein level
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1 21 2
GENE REF ISO

Function

 show evidences
Overview 
Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the putative sulfate transporter (cysz) family  9.B.7.3.1  
GO biological process 
Apoptotic processdefinition[GO:0006915]  
1
  • TASPINC
Autophagydefinition[GO:0006914] silver  
  • IEAOrtholog Compara
Intrinsic apoptotic signaling pathway in response to DNA damagedefinition[GO:0008630] silver  
  • IEAOrtholog Compara
Negative regulation of cell growthdefinition[GO:0030308]  
1
  • IDAMGI
Neuromuscular process controlling balancedefinition[GO:0050885] silver  
  • IEAOrtholog Compara
Positive regulation of intrinsic apoptotic signaling pathwaydefinition[GO:2001244] silver  
  • IEAOrtholog Compara
Response to drugdefinition[GO:0042493] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
p53 signaling pathway  hsa04115+9538  
 

Keywords

Biological process 
Apoptosis  definition   [KW-0053]
Autophagy  definition   [KW-0072]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: EI24
GenomeRNAi: 9538
PRO: PR:O14681