APOL1 - Apolipoprotein L1 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
APOL1 »  Apolipoprotein L1
 
Protein also known as:  Apolipoprotein L-I (ApoL-I).
Gene name:  APOL1
Family name: Apolipoprotein L
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 35 3
GENE REF ISO

Function

 show evidences
Overview 
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.  
  • CuratedUniProtKB
GO molecular function 
Chloride channel activitydefinition[GO:0005254]  
1
  • IDABHF-UCL
Lipid bindingdefinition[GO:0008289]  
1
  • IDABHF-UCL
Protein bindingdefinition[GO:0005515]  
1
  • IPIBHF-UCL
GO biological process 
Chloride transmembrane transportdefinition[GO:1902476]  
1
  • IDAGOC
Chloride transportdefinition[GO:0006821]  
1
  • IDABHF-UCL
Cholesterol metabolic processdefinition[GO:0008203]  
  • IEAUniProtKB KW
Cytolysisdefinition[GO:0019835]  
2
  • IDABHF-UCL
Innate immune responsedefinition[GO:0045087]  
1
  • IDABHF-UCL
Killing of cells of other organismdefinition[GO:0031640]  
2
  • IDABHF-UCL
Lipid transportdefinition[GO:0006869]  
  • IEAUniProtKB KW
Lipoprotein metabolic processdefinition[GO:0042157] silver  
  • IEAInterPro 2 GO
Pathways 
According to KEGG, this protein belongs to the following pathway:
African trypanosomiasis  hsa05143+8542  
According to Reactome, this protein belongs to the following pathway:
Scavenging of heme from plasma  REACT_160163  
 

Keywords

Biological process 
Cholesterol metabolism  definition   [KW-0153]
Lipid metabolism  definition   [KW-0443]
Lipid transport  definition   [KW-0445]
Steroid metabolism  definition   [KW-0753]
Sterol metabolism  definition   [KW-1207]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: APOL1
GenomeRNAi: 8542
PRO: PR:O14791