BACH1 - Transcription regulator protein BACH1 - human protein (Function)
 
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BACH1 »  Transcription regulator protein BACH1
 
Protein also known as:  BTB and CNC homolog 1.
Gene name:  BACH1
Family name: bZIP » CNC
Entry whose protein(s) existence is based on evidence at protein level
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1 27 1
GENE REF ISO

Function

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Overview 
Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.  
1
  • UniProtKB
GO molecular function 
Heme bindingdefinition[GO:0020037]  
1
  • UniProtKB
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptiondefinition[GO:0001078]  
2
  • UniProtKB
RNA polymerase II distal enhancer sequence-specific DNA bindingdefinition[GO:0000980] silver  
1
  • Ortholog Compara
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptiondefinition[GO:0001206] silver  
1
  • Ortholog Compara
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptiondefinition[GO:0001205] silver  
1
  • Ortholog Compara
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700]  
1
  • Ortholog Curator
GO biological process 
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122]  
1
  • UniProtKB
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
1
  • Ortholog Compara
Regulation of transcription from RNA polymerase II promoter in response to hypoxiadefinition[GO:0061418]  
1
  • UniProtKB
Regulation of transcription involved in G1/S transition of mitotic cell cycledefinition[GO:0000083]  
1
  • UniProtKB
Regulation of transcription involved in G2/M transition of mitotic cell cycledefinition[GO:0000117]  
1
  • UniProtKB
Regulation of transcription, DNA-templateddefinition[GO:0006355]  
1
  • Ortholog Curator
Transcription, DNA-templateddefinition[GO:0006351]  
1
  • UniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Repressor  definition   [KW-0678]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: BACH1
GenomeRNAi: 571
PRO: PR:O14867