UQCRQ - Cytochrome b-c1 complex subunit 8 - human protein (Function)
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UQCRQ »  Cytochrome b-c1 complex subunit 8
Protein also known as:  Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C.
Gene name:  UQCRQ
Family name: UQCRQ/QCR8
Entry whose protein(s) existence is based on evidence at protein level
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This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.  
  • CuratedUniProtKB
GO molecular function 
Ubiquinol-cytochrome-c reductase activitydefinition[GO:0008121] silver  
  • IEAInterPro 2 GO
GO biological process 
Cerebellar Purkinje cell layer developmentdefinition[GO:0021680] silver  
  • IEAOrtholog Compara
Hippocampus developmentdefinition[GO:0021766] silver  
  • IEAOrtholog Compara
Hydrogen ion transmembrane transportdefinition[GO:1902600]  
  • IEAInterPro 2 GO
Hypothalamus developmentdefinition[GO:0021854] silver  
  • IEAOrtholog Compara
Midbrain developmentdefinition[GO:0030901] silver  
  • IEAOrtholog Compara
Pons developmentdefinition[GO:0021548] silver  
  • IEAOrtholog Compara
Pyramidal neuron developmentdefinition[GO:0021860] silver  
  • IEAOrtholog Compara
Subthalamus developmentdefinition[GO:0021539] silver  
  • IEAOrtholog Compara
Thalamus developmentdefinition[GO:0021794] silver  
  • IEAOrtholog Compara
According to KEGG, this protein belongs to the following pathways:
Alzheimer's disease  hsa05010+27089  
Cardiac muscle contraction  hsa04260+27089  
Huntington's disease  hsa05016+27089  
Metabolic pathways  hsa01100+27089  
Oxidative phosphorylation  hsa00190+27089  
Parkinson's disease  hsa05012+27089  
According to Reactome, this protein belongs to the following pathway:
Respiratory electron transport  REACT_22393  


Biological process 
Electron transport  definition   [KW-0249]
Respiratory chain  definition   [KW-0679]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]

Further external links

GenomeRNAi: 27089
PRO: PR:O14949