DEGS1 - Sphingolipid delta(4)-desaturase DES1 - human protein (Function)
 
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Protein
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References

 
DEGS1 »  Sphingolipid delta(4)-desaturase DES1   [ EC 1.14.-.- ]
 
Protein also known as:  Cell migration-inducing gene 15 protein.
Gene name:  DEGS1
Family name: Fatty acid desaturase » DEGS
Entry whose protein(s) existence is based on evidence at protein level
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1 21 1
GENE REF ISO

Function

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Overview 
Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).  
1
  • CuratedUniProtKB
GO molecular function 
Electron carrier activitydefinition[GO:0009055]  
1
  • TASUniProtKB
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygendefinition[GO:0016705] silver  
  • IEAInterPro 2 GO
GO biological process 
Unsaturated fatty acid biosynthetic processdefinition[GO:0006636]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
Metabolic pathways  hsa01100+8560  
Sphingolipid metabolism  hsa00600+8560  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Biological process 
Fatty acid biosynthesis  definition   [KW-0275]
Fatty acid metabolism  definition   [KW-0276]
Lipid biosynthesis  definition   [KW-0444]
Lipid metabolism  definition   [KW-0443]
Molecular function 
Oxidoreductase  definition   [KW-0560]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 8560
PRO: PR:O15121