EPHB6 - Ephrin type-B receptor 6 - human protein (Function)
 
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Protein
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References

 
EPHB6 »  Ephrin type-B receptor 6
 
Protein also known as:  Tyrosine-protein kinase-defective receptor EPH-6.
Gene name:  EPHB6
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.  
2
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Ephrin receptor activitydefinition[GO:0005003] silver  
  • IEAInterPro 2 GO
Receptor activitydefinition[GO:0004872]  
1
  • TASPINC
GO biological process 
Calcium ion homeostasisdefinition[GO:0055074] silver  
  • IEAOrtholog Compara
Parathyroid hormone secretiondefinition[GO:0035898] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Axon guidance  hsa04360+2051  
 

Keywords

Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: EPHB6
GenomeRNAi: 2051
PRO: PR:O15197
Chemistry
GuidetoPHARMACOLOGY: 1834