FANCG - Fanconi anemia group G protein - human protein (Function)
 
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Protein
Gene
References

 
FANCG »  Fanconi anemia group G protein
 
Gene name:  FANCG
Entry whose protein(s) existence is based on evidence at protein level
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1 62 1
GENE REF ISO

Function

 show evidences
Overview 
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.  
  • CuratedUniProtKB
GO molecular function 
Damaged DNA bindingdefinition[GO:0003684]  
1
  • TASPINC
Protein bindingdefinition[GO:0005515]  
8
  • IPIIntAct
  • IPIUniProtKB
GO biological process 
Cell cycle checkpointdefinition[GO:0000075]  
1
  • TASPINC
Mitochondrion organizationdefinition[GO:0007005]  
1
  • IMPUniProtKB
Ovarian follicle developmentdefinition[GO:0001541] silver  
  • IEAOrtholog Compara
Response to radiationdefinition[GO:0009314] silver  
  • IEAOrtholog Compara
Spermatid developmentdefinition[GO:0007286] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Fanconi anemia pathway  hsa03460+2189  
According to Reactome, this protein belongs to the following pathway:
Fanconi Anemia pathway  REACT_18410  
 

Keywords

Biological process 
DNA damage  definition   [KW-0227]
DNA repair  definition   [KW-0234]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FANCG
GenomeRNAi: 2189
PRO: PR:O15287