GPR37 - Prosaposin receptor GPR37 - human protein (Function)
 
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Protein
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References

 
GPR37 »  Prosaposin receptor GPR37
 
Protein also known as:  Parkin-associated endothelin receptor-like receptor (PAELR).
Gene name:  GPR37
Entry whose protein(s) existence is based on evidence at protein level
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1 35 1
GENE REF ISO

Function

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Overview 
Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.  
3
  • CuratedUniProtKB
GO molecular function 
G-protein coupled receptor activitydefinition[GO:0004930]  
  • IEAUniProtKB KW
GO biological process 
G-protein coupled receptor signaling pathwaydefinition[GO:0007186]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Parkinson's disease  hsa05012+2861  
 

Keywords

Molecular function 
G-protein coupled receptor  definition   [KW-0297]
Receptor  definition   [KW-0675]
Transducer  definition   [KW-0807]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: GPR37
GenomeRNAi: 2861
PRO: PR:O15354
Chemistry
GuidetoPHARMACOLOGY: 103