FANCA - Fanconi anemia group A protein - human protein (Function)
 
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Protein
Gene
References

 
FANCA »  Fanconi anemia group A protein  (Protein FACA)
 
Gene name:  FANCA
Entry whose protein(s) existence is based on evidence at protein level
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1 97 3
GENE REF ISO

Function

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Overview 
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  
  • CuratedUniProtKB
GO molecular function 
Protein bindingdefinition[GO:0005515]  
11
  • IPIUniProtKB
  • IPIIntAct
  • IPIBHF-UCL
GO biological process 
Female gonad developmentdefinition[GO:0008585] silver  
  • IEAOrtholog Compara
Male gonad developmentdefinition[GO:0008584] silver  
  • IEAOrtholog Compara
Male meiosisdefinition[GO:0007140] silver  
  • IEAOrtholog Compara
Protein complex assemblydefinition[GO:0006461]  
1
  • TASPINC
Regulation of cell proliferationdefinition[GO:0042127] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Fanconi anemia pathway  hsa03460+2175  
According to Reactome, this protein belongs to the following pathway:
DNA Repair  REACT_216  
 

Keywords

Biological process 
DNA damage  definition   [KW-0227]
DNA repair  definition   [KW-0234]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FANCA
GenomeRNAi: 2175
PRO: PR:O15360