ABCC3 - Canalicular multispecific organic anion transporter 2 - human protein (Function)
 
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Protein
Gene
References

 
ABCC3 »  Canalicular multispecific organic anion transporter 2
 
Protein also known as:  ATP-binding cassette sub-family C member 3.
Gene name:  ABCC3
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 62 5
GENE REF ISO

Function

 show evidences
Overview 
May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity).  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the atp-binding cassette (abc) superfamily  3.A.1.208.9  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
ATPase activity, coupled to transmembrane movement of substancesdefinition[GO:0042626] silver  
  • IEAInterPro 2 GO
Organic anion transmembrane transporter activitydefinition[GO:0008514]  
1
  • TASPINC
GO biological process 
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathways:
ABC transporters  hsa02010+8714  
Bile secretion  hsa04976+8714  
According to Reactome, this protein belongs to the following pathways:
Metabolism  REACT_111217  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ABCC3
GenomeRNAi: 8714
PRO: PR:O15438