RGS5 - Regulator of G-protein signaling 5 - human protein (Function)
 
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RGS5 »  Regulator of G-protein signaling 5  (RGS5)
 
Gene name:  RGS5
Entry whose protein(s) existence is based on evidence at protein level
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1 20 3
GENE REF ISO

Function

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Overview 
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).  
  • CuratedUniProtKB
GO molecular function 
GTPase activator activitydefinition[GO:0005096] silver  
  • IBARefGenome
GO biological process 
Positive regulation of catalytic activitydefinition[GO:0043085]  
1
  • TASGOC
  • IBARefGenome
Positive regulation of GTPase activitydefinition[GO:0043547]  
1
  • TASGOC
  • IBARefGenome
Regulation of catalytic activitydefinition[GO:0050790]  
1
  • TASGOC
  • IBARefGenome
Regulation of G-protein coupled receptor protein signaling pathwaydefinition[GO:0008277]  
1
  • TASPINC
Signal transductiondefinition[GO:0007165] silver  
  • IEAOrtholog Compara
Termination of G-protein coupled receptor signaling pathwaydefinition[GO:0038032] silver  
  • IEAInterPro 2 GO
 

Keywords

Molecular function 
Signal transduction inhibitor  definition   [KW-0734]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: RGS5
GenomeRNAi: 8490
PRO: PR:O15539