MSH5 - MutS protein homolog 5 - human protein (Function)
 
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Protein
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References

 
MSH5 »  MutS protein homolog 5
 
Gene name:  MSH5
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 36 4
GENE REF ISO

Function

 show evidences
Overview 
Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis (By similarity).  
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
Not  Damaged DNA bindingdefinition[GO:0003684] silver  
  • IRDRefGenome
DNA-dependent ATPase activitydefinition[GO:0008094] silver  
  • IBARefGenome
Mismatched DNA bindingdefinition[GO:0030983] silver  
  • IBARefGenome
Protein bindingdefinition[GO:0005515]  
3
  • IPIIntAct
GO biological process 
ATP catabolic processdefinition[GO:0006200] silver  
  • IBARefGenome
Chiasma assemblydefinition[GO:0051026] silver  
  • IBARefGenome
Homologous chromosome segregationdefinition[GO:0045143] silver  
  • IBARefGenome
Not  Meiotic mismatch repairdefinition[GO:0000710] silver  
  • IRDRefGenome
Meiotic nuclear divisiondefinition[GO:0007126]  
1
  • TASPINC
Meiotic prophase IIdefinition[GO:0007136]  
1
  • TASPINC
Mismatch repairdefinition[GO:0006298]  
1
  • TASPINC
Reciprocal meiotic recombinationdefinition[GO:0007131] silver  
  • IBARefGenome
Pathways 
According to Reactome, this protein belongs to the following pathway:
Meiotic recombination  REACT_27271  
 

Keywords

Biological process 
Meiosis  definition   [KW-0469]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MSH5
GenomeRNAi: 4439
PRO: PR:O43196