MSH5 - MutS protein homolog 5 - human protein (Function)
 
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MSH5 »  MutS protein homolog 5
 
Gene name:  MSH5
Entry whose protein(s) existence is based on evidence at protein level
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1 38 4
GENE REF ISO

Function

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Overview 
Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis (By similarity).  
1
  • UniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • UniProtKB KW
Not  Damaged DNA bindingdefinition[GO:0003684]  
1
  • RefGenome
DNA-dependent ATPase activitydefinition[GO:0008094]  
1
  • RefGenome
Mismatched DNA bindingdefinition[GO:0030983]  
1
  • RefGenome
Protein bindingdefinition[GO:0005515]  
3
  • IntAct
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
1
  • RefGenome
Chiasma assemblydefinition[GO:0051026]  
1
  • RefGenome
Homologous chromosome segregationdefinition[GO:0045143]  
1
  • RefGenome
Not  Meiotic mismatch repairdefinition[GO:0000710]  
1
  • RefGenome
Reciprocal meiotic recombinationdefinition[GO:0007131]  
1
  • RefGenome
Pathways 
According to Reactome, this protein belongs to the following pathway:
Meiotic recombination  REACT_27271  
 

Keywords

Biological process 
Meiosis  definition   [KW-0469]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: MSH5
GenomeRNAi: 4439
PRO: PR:O43196