B4GALT5 - Beta-1,4-galactosyltransferase 5 - human protein (Function)
 
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Protein
Gene
References

 
B4GALT5 »  Beta-1,4-galactosyltransferase 5   [ EC 2.4.1.- ]  (b4Gal-T5)
 
Protein also known as:  UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5.
Gene name:  B4GALT5
Family name: Glycosyltransferase 7
Entry whose protein(s) existence is based on evidence at protein level
extend overview
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GENE REF ISO

Function

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Overview 
Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.  
1
  • CuratedUniProtKB
GO molecular function 
Galactosyltransferase activitydefinition[GO:0008378]  
1
  • TASPINC
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Enzymatic activity 
It requires the following cofactor
Manganese (By similarity).  
  • CuratedUniProtKB
According to CAZy, this protein is belongs to the following pathway:
Glycosyltransferase Family 7  GT7  
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathway:
Mucin type O-Glycan biosynthesis  hsa00512+9334  
According to Reactome, this protein belongs to the following pathways:
Keratan sulfate biosynthesis  REACT_121120  
N-Glycan antennae elongation  REACT_25085  
O-linked glycosylation of mucins  REACT_115606  
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: B4GALT5
GenomeRNAi: 9334
PRO: PR:O43286