HOXA2 - Homeobox protein Hox-A2 - human protein (Function)
 
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HOXA2 »  Homeobox protein Hox-A2
 
Protein also known as:  Homeobox protein Hox-1K.
Gene name:  HOXA2
Family name: Antp homeobox » Proboscipedia
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  
  • CuratedUniProtKB
GO molecular function 
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAOrtholog Compara
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Anterior/posterior pattern specificationdefinition[GO:0009952] silver  
  • IEAOrtholog Compara
Brain segmentationdefinition[GO:0035284] silver  
  • IEAOrtholog Compara
Cell fate determinationdefinition[GO:0001709] silver  
  • IEAOrtholog Compara
Dorsal/ventral pattern formationdefinition[GO:0009953] silver  
  • IEAOrtholog Compara
Embryonic viscerocranium morphogenesisdefinition[GO:0048703] silver  
  • IEAOrtholog Compara
Middle ear morphogenesisdefinition[GO:0042474] silver  
  • IEAOrtholog Compara
Motor neuron axon guidancedefinition[GO:0008045] silver  
  • IEAOrtholog Compara
Negative regulation of neuron differentiationdefinition[GO:0045665] silver  
  • IEAOrtholog Compara
Negative regulation of transcription from RNA polymerase II promoterdefinition[GO:0000122] silver  
  • IEAOrtholog Compara
Osteoblast developmentdefinition[GO:0002076] silver  
  • IEAOrtholog Compara
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Rhombomere 2 developmentdefinition[GO:0021568] silver  
  • IEAOrtholog Compara
Rhombomere 3 morphogenesisdefinition[GO:0021658] silver  
  • IEAOrtholog Compara
Segment specificationdefinition[GO:0007379] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Developmental protein  definition   [KW-0217]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: HOXA2
GenomeRNAi: 3199
PRO: PR:O43364