XRCC3 - DNA repair protein XRCC3 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
XRCC3 »  DNA repair protein XRCC3
 
Protein also known as:  X-ray repair cross-complementing protein 3.
Gene name:  XRCC3
Family name: RecA » RAD51
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 121 1
GENE REF ISO

Function

 show evidences
Overview 
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.  
1
  • CuratedUniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
DNA bindingdefinition[GO:0003677]  
  • IEAUniProtKB KW
DNA-dependent ATPase activitydefinition[GO:0008094] silver  
  • IEAInterPro 2 GO
Protein bindingdefinition[GO:0005515]  
1
  • IPIIntAct
GO biological process 
Cellular response to DNA damage stimulusdefinition[GO:0006974]  
1
  • TASPINC
DNA recombinationdefinition[GO:0006310]  
  • IEAUniProtKB KW
DNA repairdefinition[GO:0006281]  
1
  • IGIBHF-UCL
Response to organic substancedefinition[GO:0010033] silver  
  • IEAOrtholog Compara
Pathways 
According to KEGG, this protein belongs to the following pathway:
Homologous recombination  hsa03440+7517  
 

Keywords

Biological process 
DNA damage  definition   [KW-0227]
DNA recombination  definition   [KW-0233]
DNA repair  definition   [KW-0234]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: XRCC3
GenomeRNAi: 7517
PRO: PR:O43542