RGS10 - Regulator of G-protein signaling 10 - human protein (Function)
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RGS10 »  Regulator of G-protein signaling 10  (RGS10)
Gene name:  RGS10
Entry whose protein(s) existence is based on evidence at protein level
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Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.  
  • CuratedUniProtKB
GO molecular function 
GTPase activator activitydefinition[GO:0005096] silver  
  • IBARefGenome
GO biological process 
Positive regulation of catalytic activitydefinition[GO:0043085] silver  
  • IBARefGenome
Positive regulation of GTPase activitydefinition[GO:0043547] silver  
  • IBARefGenome
Regulation of catalytic activitydefinition[GO:0050790] silver  
  • IBARefGenome
Termination of G-protein coupled receptor signaling pathwaydefinition[GO:0038032] silver  
  • IEAInterPro 2 GO


Molecular function 
Signal transduction inhibitor  definition   [KW-0734]
Technical term 
Reference proteome  definition   [KW-1185]

Further external links

GeneWiki: RGS10
GenomeRNAi: 6001
PRO: PR:O43665