B3GALT2 - Beta-1,3-galactosyltransferase 2 - human protein (Function)
 
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Protein
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References

 
B3GALT2 »  Beta-1,3-galactosyltransferase 2   [ EC 2.4.1.- ]  (Beta3GalT2)
 
Protein also known as:  UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2.
Gene name:  B3GALT2
Family name: Glycosyltransferase 31
Entry whose protein(s) existence is based on evidence at transcript level
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1 16 1
GENE REF ISO

Function

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Overview 
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N-acetylglucosamine (beta-GlcNAc) residue. Can also utilize substrates with a terminal galactose residue, albeit with lower efficiency. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N-acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues.  
2
  • CuratedUniProtKB
GO molecular function 
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activitydefinition[GO:0008499] silver  
  • IEAOrtholog Compara
GO biological process 
Oligosaccharide biosynthetic processdefinition[GO:0009312] silver  
  • IEAOrtholog Compara
Protein glycosylationdefinition[GO:0006486]  
  • IEAUniPathway
Enzymatic activity 
It requires the following cofactor
Manganese (By similarity).  
  • CuratedUniProtKB
According to CAZy, this protein is belongs to the following pathway:
Glycosyltransferase Family 31  GT31  
 
More information is available from:
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycosphingolipid biosynthesis - lacto and neolacto series  hsa00601+8707  
Metabolic pathways  hsa01100+8707  
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 8707
PRO: PR:O43825