PEX1 - Peroxisome biogenesis factor 1 - human protein (Function)
 
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Protein
Gene
References

 
PEX1 »  Peroxisome biogenesis factor 1
 
Protein also known as:  Peroxisome biogenesis disorder protein 1.
Gene name:  PEX1
Family name: AAA ATPase
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 49 1
GENE REF ISO

Function

 show evidences
Overview 
Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the peroxisomal protein importer (ppi) family  3.A.20.1.1  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • IMPUniProtKB
ATPase activity, coupleddefinition[GO:0042623]  
1
  • IMPUniProtKB
Protein bindingdefinition[GO:0005515]  
2
  • IPIUniProtKB
  • IPIIntAct
Protein C-terminus bindingdefinition[GO:0008022]  
1
  • IPIUniProtKB
Protein complex bindingdefinition[GO:0032403]  
1
  • IDAUniProtKB
GO biological process 
ATP catabolic processdefinition[GO:0006200]  
1
  • IMPGOC
Metabolic processdefinition[GO:0008152]  
1
  • IMPGOC
Microtubule-based peroxisome localizationdefinition[GO:0060152]  
1
  • IMPUniProtKB
Peroxisome organizationdefinition[GO:0007031]  
1
  • IMPUniProtKB
Protein import into peroxisome matrixdefinition[GO:0016558]  
1
  • IMPUniProtKB
Protein targeting to peroxisomedefinition[GO:0006625]  
2
  • IMPUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Peroxisome  hsa04146+5189  
 

Keywords

Biological process 
Peroxisome biogenesis  definition   [KW-0962]
Protein transport  definition   [KW-0653]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: PEX1
GenomeRNAi: 5189
PRO: PR:O43933