CREBL2 - cAMP-responsive element-binding protein-like 2 - human protein (Function)
 
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CREBL2 »  cAMP-responsive element-binding protein-like 2
 
Gene name:  CREBL2
Family name: bZIP » ATF
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor.  
1
  • CuratedUniProtKB
GO molecular function 
Sequence-specific DNA bindingdefinition[GO:0043565] silver  
  • IEAInterPro 2 GO
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell cycledefinition[GO:0007049]  
  • IEAUniProtKB KW
Cell differentiationdefinition[GO:0030154]  
  • IEAUniProtKB KW
Positive regulation of fat cell differentiationdefinition[GO:0045600]  
  • ISSOrtholog Curator
Positive regulation of glucose importdefinition[GO:0046326]  
  • ISSOrtholog Curator
Positive regulation of lipid biosynthetic processdefinition[GO:0046889]  
  • ISSOrtholog Curator
Positive regulation of peptidyl-serine phosphorylationdefinition[GO:0033138]  
  • ISSOrtholog Curator
Positive regulation of transcription, DNA-templateddefinition[GO:0045893]  
  • ISSOrtholog Curator
Protein stabilizationdefinition[GO:0050821]  
  • ISSOrtholog Curator
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Cell cycle  definition   [KW-0131]
Differentiation  definition   [KW-0221]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Activator  definition   [KW-0010]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 1389
PRO: PR:O60519