SLC16A7 - Monocarboxylate transporter 2 - human protein (Function)
 
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Protein
Gene
References

 
SLC16A7 »  Monocarboxylate transporter 2  (MCT 2)
 
Protein also known as:  Solute carrier family 16 member 7.
Gene name:  SLC16A7
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.  
1
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the major facilitator superfamily (mfs)  2.A.1.13.5  
GO molecular function 
Lactate transmembrane transporter activitydefinition[GO:0015129]  
1
  • IDAUniProtKB
Pyruvate secondary active transmembrane transporter activitydefinition[GO:0005477]  
1
  • TASPINC
Pyruvate transmembrane transporter activitydefinition[GO:0050833]  
1
  • IDAUniProtKB
Secondary active monocarboxylate transmembrane transporter activitydefinition[GO:0015355] silver  
  • IEAInterPro 2 GO
Symporter activitydefinition[GO:0015293]  
  • IEAUniProtKB KW
GO biological process 
Lactate transmembrane transportdefinition[GO:0035873]  
1
  • IMPUniProtKB
Pyruvate transmembrane transportdefinition[GO:1901475]  
1
  • IDAUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathways:
Bile salt and organic anion SLC transporters  REACT_20633  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Symport  definition   [KW-0769]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Enzyme and pathway databases
SABIO-RK: O60669
Other
GenomeRNAi: 9194
PRO: PR:O60669