DKC1 - H/ACA ribonucleoprotein complex subunit 4 - human protein (Function)
 
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DKC1 »  H/ACA ribonucleoprotein complex subunit 4   [ EC 5.4.99.- ]
 
Protein also known as:  Nopp140-associated protein of 57 kDa.
Gene name:  DKC1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

 show evidences
GO molecular function 
Poly(A) RNA bindingdefinition[GO:0044822]  
1
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
6
  • IntAct
  • UniProtKB
Pseudouridine synthase activitydefinition[GO:0009982]  
1
  • RefGenome
RNA bindingdefinition[GO:0003723]  
1
  • PINC
Telomerase activitydefinition[GO:0003720]  
1
  • UniProtKB
GO biological process 
Box H/ACA snoRNA 3'-end processingdefinition[GO:0000495]  
1
  • RefGenome
Cell proliferationdefinition[GO:0008283]  
1
  • PINC
mRNA pseudouridine synthesisdefinition[GO:1990481]  
1
  • RefGenome
RNA processingdefinition[GO:0006396]  
1
  • PINC
rRNA processingdefinition[GO:0006364]  
1
  • PINC
rRNA pseudouridine synthesisdefinition[GO:0031118]  
1
  • RefGenome
snRNA pseudouridine synthesisdefinition[GO:0031120]  
1
  • RefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 5.4.99.-: RNA uridine RNA pseudouridine.  
1
  • UniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Ribosome biogenesis in eukaryotes  hsa03008+1736  
According to Reactome, this protein belongs to the following pathway:
Telomere Extension By Telomerase  REACT_7974  
 

Keywords

Biological process 
Ribosome biogenesis  definition   [KW-0690]
rRNA processing  definition   [KW-0698]
Molecular function 
Isomerase  definition   [KW-0413]
Ribonucleoprotein  definition   [KW-0687]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Dyskerin
GenomeRNAi: 1736
PRO: PR:O60832