ABCB7 - ATP-binding cassette sub-family B member 7, mitochondrial - human protein (Function)
 
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Protein
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References

 
ABCB7 »  ATP-binding cassette sub-family B member 7, mitochondrial
 
Protein also known as:  ATP-binding cassette transporter 7 (ABC transporter 7 protein).
Gene name:  ABCB7
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 29 3
GENE REF ISO

Function

 show evidences
Overview 
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the atp-binding cassette (abc) superfamily  3.A.1.210.4  
GO molecular function 
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
ATPase activity, coupled to transmembrane movement of substancesdefinition[GO:0042626] silver  
  • IBARefGenome
Heme transporter activitydefinition[GO:0015232]  
1
  • TASPINC
GO biological process 
Cellular iron ion homeostasisdefinition[GO:0006879] silver  
  • IBARefGenome
Heme transportdefinition[GO:0015886]  
1
  • TASGOC
Transmembrane transportdefinition[GO:0055085] silver  
  • IBARefGenome
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
ABC transporters  hsa02010+22  
According to Reactome, this protein belongs to the following pathways:
Metabolism  REACT_111217  
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ABCB7
GenomeRNAi: 22
PRO: PR:O75027