CBFA2T3 - Protein CBFA2T3 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
CBFA2T3 »  Protein CBFA2T3
 
Protein also known as:  Myeloid translocation gene on chromosome 16 protein.
Gene name:  CBFA2T3
Family name: CBFA2T
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 43 4
GENE REF ISO

Function

 show evidences
Overview 
Functions as a transcriptional repressor. Regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. Plays a role in granulocyte differentiation.  
4
  • CuratedUniProtKB
Isoform  Iso 2   Functions as an A-kinase-anchoring protein.  
4
  • CuratedUniProtKB
GO molecular function 
Chromatin bindingdefinition[GO:0003682] silver  
  • IEAOrtholog Compara
Metal ion bindingdefinition[GO:0046872]  
  • IEAUniProtKB KW
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
Sequence-specific DNA binding transcription factor activitydefinition[GO:0003700] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell proliferationdefinition[GO:0008283]  
1
  • TASPINC
Granulocyte differentiationdefinition[GO:0030851]  
1
  • IDAMGI
Positive regulation of transcription from RNA polymerase II promoterdefinition[GO:0045944] silver  
  • IEAOrtholog Compara
Transcription, DNA-templateddefinition[GO:0006351]  
  • IEAUniProtKB KW
 

Keywords

Biological process 
Differentiation  definition   [KW-0221]
Transcription  definition   [KW-0804]
Transcription regulation  definition   [KW-0805]
Molecular function 
Repressor  definition   [KW-0678]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CBFA2T3
GenomeRNAi: 863
PRO: PR:O75081