ATP6V1G1 - V-type proton ATPase subunit G 1 - human protein (Function)
 
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ATP6V1G1 »  V-type proton ATPase subunit G 1  (V-ATPase subunit G 1)
 
Protein also known as:  Vacuolar proton pump subunit M16.
Gene name:  ATP6V1G1
Family name: V-ATPase G subunit
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 19 1
GENE REF ISO

Function

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Overview 
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily  3.A.2.2.4  
GO molecular function 
ATPase bindingdefinition[GO:0051117]  
1
  • IPIUniProtKB
Hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesdefinition[GO:0016820] silver  
  • IEAInterPro 2 GO
GO biological process 
Proton transportdefinition[GO:0015992]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathways:
Collecting duct acid secretion  hsa04966+9550  
Epithelial cell signaling in Helicobacter pylori infection  hsa05120+9550  
Metabolic pathways  hsa01100+9550  
Oxidative phosphorylation  hsa00190+9550  
Phagosome  hsa04145+9550  
Rheumatoid arthritis  hsa05323+9550  
Synaptic vesicle cycle  hsa04721+9550  
Vibrio cholerae infection  hsa05110+9550  
According to Reactome, this protein belongs to the following pathways:
Disease  REACT_116125  
Signal Transduction  REACT_111102  
Transmembrane transport of small molecules  REACT_15518  
 
More information is available from:
 

Keywords

Biological process 
Hydrogen ion transport  definition   [KW-0375]
Ion transport  definition   [KW-0406]
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: ATP6V1G1
GenomeRNAi: 9550
PRO: PR:O75348