CRLF1 - Cytokine receptor-like factor 1 - human protein (Function)
 
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Protein
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References

 
CRLF1 »  Cytokine receptor-like factor 1
 
Gene name:  CRLF1
Entry whose protein(s) existence is based on evidence at protein level
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1 24 1
GENE REF ISO

Function

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Overview 
Cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. May be involved in nervous system development.  
  • CuratedUniProtKB
GO molecular function 
Contributes to ciliary neurotrophic factor receptor bindingdefinition[GO:0005127]  
1
  • IDABHF-UCL
Contributes to cytokine activitydefinition[GO:0005125]  
1
  • IDABHF-UCL
Cytokine bindingdefinition[GO:0019955]  
1
  • IPIHGNC
Protein bindingdefinition[GO:0005515]  
1
  • IPIBHF-UCL
Protein heterodimerization activitydefinition[GO:0046982]  
1
  • IDABHF-UCL
Receptor activitydefinition[GO:0004872]  
1
  • TASPINC
GO biological process 
Negative regulation of motor neuron apoptotic processdefinition[GO:2000672] silver  
  • IEAOrtholog Compara
Negative regulation of neuron apoptotic processdefinition[GO:0043524]  
1
  • IDABHF-UCL
Positive regulation of cell proliferationdefinition[GO:0008284]  
1
  • IDABHF-UCL
Positive regulation of tyrosine phosphorylation of Stat3 proteindefinition[GO:0042517]  
1
  • IDABHF-UCL
Ureteric bud developmentdefinition[GO:0001657] silver  
  • IEAOrtholog Compara
 

Keywords

Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CRLF1
GenomeRNAi: 9244
PRO: PR:O75462