ADAP1 - Arf-GAP with dual PH domain-containing protein 1 - human protein (Function)
 
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ADAP1 »  Arf-GAP with dual PH domain-containing protein 1
 
Protein also known as:  Putative MAPK-activating protein PM25.
Gene name:  ADAP1
Entry whose protein(s) existence is based on evidence at protein level
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1 35 3
GENE REF ISO

Function

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Overview 
GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).  
2
  • CuratedUniProtKB
GO molecular function 
ARF GTPase activator activitydefinition[GO:0008060]  
2
  • IDAUniProtKB
Inositol 1,3,4,5 tetrakisphosphate bindingdefinition[GO:0043533]  
1
  • TASUniProtKB
Phosphatidylinositol-3,4,5-trisphosphate bindingdefinition[GO:0005547] silver  
  • IEAOrtholog Compara
Protein bindingdefinition[GO:0005515]  
1
  • IPIUniProtKB
Zinc ion bindingdefinition[GO:0008270] silver  
  • IEAInterPro 2 GO
GO biological process 
Cell surface receptor signaling pathwaydefinition[GO:0007166]  
1
  • TASPINC
Positive regulation of GTPase activitydefinition[GO:0043547]  
2
  • IDAGOC
Regulation of ARF GTPase activitydefinition[GO:0032312] silver  
  • IEAInterPro 2 GO
Regulation of GTPase activitydefinition[GO:0043087]  
1
  • IMPUniProtKB
 

Keywords

Molecular function 
GTPase activation  definition   [KW-0343]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: Centaurin,_alpha_1
GenomeRNAi: 11033
PRO: PR:O75689