NCR1 - Natural cytotoxicity triggering receptor 1 - human protein (Function)
 
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Protein
Gene
References

 
NCR1 »  Natural cytotoxicity triggering receptor 1
 
Protein also known as:  Natural killer cell p46-related protein (NKp46); CD antigen CD335.
Gene name:  NCR1
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.  
1
  • CuratedUniProtKB
GO molecular function 
Receptor signaling protein activitydefinition[GO:0005057]  
1
  • TASPINC
GO biological process 
Cellular defense responsedefinition[GO:0006968]  
1
  • TASPINC
Intracellular signal transductiondefinition[GO:0035556]  
1
  • TASGOC
Natural killer cell activationdefinition[GO:0030101]  
1
  • NASUniProtKB
Regulation of natural killer cell mediated cytotoxicitydefinition[GO:0042269]  
1
  • TASUniProtKB
Signal transductiondefinition[GO:0007165]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Natural killer cell mediated cytotoxicity  hsa04650+9437  
 

Keywords

Molecular function 
Receptor  definition   [KW-0675]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: NCR1
GenomeRNAi: 9437
PRO: PR:O76036