AQP8 - Aquaporin-8 - human protein (Function)
 
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Protein
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AQP8 »  Aquaporin-8  (AQP-8)
 
Gene name:  AQP8
Entry whose protein(s) existence is based on evidence at protein level
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1 26 1
GENE REF ISO

Function

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Overview 
Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the major intrinsic protein (mip) family  1.A.8.16.1  
GO molecular function 
Water channel activitydefinition[GO:0015250]  
1
  • TASPINC
GO biological process 
Canalicular bile acid transportdefinition[GO:0015722] silver  
  • IEAOrtholog Compara
Cellular response to cAMPdefinition[GO:0071320]  
1
  • IEPUniProtKB
Transportdefinition[GO:0006810]  
1
  • TASPINC
Pathways 
According to KEGG, this protein belongs to the following pathway:
Bile secretion  hsa04976+343  
According to Reactome, this protein belongs to the following pathway:
Transmembrane transport of small molecules  REACT_15518  
 

Keywords

Biological process 
Transport  definition   [KW-0813]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: AQP8
GenomeRNAi: 343
PRO: PR:O94778
Chemistry
GuidetoPHARMACOLOGY: 695