LETM1 - LETM1 and EF-hand domain-containing protein 1, mitochondrial - human protein (Function)
 
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LETM1 »  LETM1 and EF-hand domain-containing protein 1, mitochondrial
 
Protein also known as:  Leucine zipper-EF-hand-containing transmembrane protein 1.
Gene name:  LETM1
Entry whose protein(s) existence is based on evidence at protein level
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1 37 3
GENE REF ISO

Function

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Overview 
Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.  
2
  • UniProtKB
According to TCDB this is a transporter from family:
the mitochondrial inner membrane k(+)/h(+) and ca(2+)/h(+) exchanger (letm1) family  2.A.97.1.1  
GO molecular function 
Calcium ion bindingdefinition[GO:0005509] silver  
1
  • InterPro 2 GO
Protein bindingdefinition[GO:0005515]  
2
  • IntAct
  • UniProtKB
GO biological process 
Cristae formationdefinition[GO:0042407]  
1
  • UniProtKB
 

Keywords

Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: LETM1
GenomeRNAi: 3954
PRO: PR:O95202