KCNH1 - Potassium voltage-gated channel subfamily H member 1 - human protein (Function)
 
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Protein
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References

 
KCNH1 »  Potassium voltage-gated channel subfamily H member 1
 
Protein also known as:  Voltage-gated potassium channel subunit Kv10.1.
Gene name:  KCNH1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 69 2
GENE REF ISO

Function

 show evidences
Overview 
Pore-forming (alpha) subunit of voltage-gated non-inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts.  
  • CuratedUniProtKB
GO molecular function 
Calmodulin bindingdefinition[GO:0005516]  
  • IEAUniProtKB KW
Delayed rectifier potassium channel activitydefinition[GO:0005251]  
1
  • TASPINC
Phosphorelay sensor kinase activitydefinition[GO:0000155] silver  
  • IEAInterPro 2 GO
Protein bindingdefinition[GO:0005515]  
2
  • IPIIntAct
GO biological process 
Myoblast fusiondefinition[GO:0007520]  
1
  • TASPINC
Phosphorelay signal transduction systemdefinition[GO:0000160] silver  
  • IEAInterPro 2 GO
Potassium ion transmembrane transportdefinition[GO:0071805] silver  
  • IBARefGenome
Potassium ion transportdefinition[GO:0006813]  
1
  • TASPINC
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • IEAUniProtKB KW
Regulation of membrane potentialdefinition[GO:0042391] silver  
  • IBARefGenome
Signal transduction by phosphorylationdefinition[GO:0023014]  
  • IEAInterPro 2 GO
Pathways 
According to Reactome, this protein belongs to the following pathway:
Voltage gated Potassium channels  REACT_75770  
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: KCNH1
GenomeRNAi: 3756
PRO: PR:O95259
Chemistry
GuidetoPHARMACOLOGY: 570