KCNK5 - Potassium channel subfamily K member 5 - human protein (Function)
 
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Protein
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KCNK5 »  Potassium channel subfamily K member 5
 
Protein also known as:  Acid-sensitive potassium channel protein TASK-2.
Gene name:  KCNK5
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
PH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.  
  • CuratedUniProtKB
According to TCDB this is a transporter from family:
the voltage-gated ion channel (vic) superfamily  1.A.1.8.2  
GO molecular function 
Potassium channel activitydefinition[GO:0005267]  
  • IEAUniProtKB KW
Voltage-gated ion channel activitydefinition[GO:0005244]  
  • IEAUniProtKB KW
GO biological process 
Excretiondefinition[GO:0007588]  
1
  • TASPINC
Potassium ion transmembrane transportdefinition[GO:0071805]  
  • IEAUniProtKB KW
Potassium ion transportdefinition[GO:0006813]  
1
  • TASPINC
Regulation of ion transmembrane transportdefinition[GO:0034765]  
  • IEAUniProtKB KW
Pathways 
According to KEGG, this protein belongs to the following pathway:
Protein digestion and absorption  hsa04974+8645  
Note 
Inhibited by quinine, quinidine and external acidification.  
  • CuratedUniProtKB
 

Keywords

Biological process 
Ion transport  definition   [KW-0406]
Potassium transport  definition   [KW-0633]
Transport  definition   [KW-0813]
Molecular function 
Ion channel  definition   [KW-0407]
Potassium channel  definition   [KW-0631]
Voltage-gated channel  definition   [KW-0851]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: KCNK5
GenomeRNAi: 8645
PRO: PR:O95279