FKBP9 - Peptidyl-prolyl cis-trans isomerase FKBP9 - human protein (Function)
 
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FKBP9 »  Peptidyl-prolyl cis-trans isomerase FKBP9   [ EC 5.2.1.8 ]  (PPIase FKBP9)
 
Protein also known as:  63 kDa FK506-binding protein (FKBP-63).
Gene name:  FKBP9
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
PPIases accelerate the folding of proteins during protein synthesis.  
  • CuratedUniProtKB
GO molecular function 
Calcium ion bindingdefinition[GO:0005509]  
  • ISSOrtholog Curator
FK506 bindingdefinition[GO:0005528] silver  
  • IBARefGenome
Peptidyl-prolyl cis-trans isomerase activitydefinition[GO:0003755] silver  
  • IBARefGenome
GO biological process 
Chaperone-mediated protein foldingdefinition[GO:0061077] silver  
  • IBARefGenome
Protein foldingdefinition[GO:0006457]  
  • ISSOrtholog Curator
Protein peptidyl-prolyl isomerizationdefinition[GO:0000413] silver  
  • IBARefGenome
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 5.2.1.8: Peptidylproline (omega180) peptidylproline (omega0).  
  • CuratedUniProtKB
It is regulated in the following manner
Inhibited by FK506 (By similarity).  
  • CuratedUniProtKB
Pathways 
According to Reactome, this protein belongs to the following pathway:
Association of TriC/CCT with target proteins during biosynthesis  REACT_16907  
 

Keywords

Molecular function 
Isomerase  definition   [KW-0413]
Rotamase  definition   [KW-0697]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: FKBP9
GenomeRNAi: 11328
PRO: PR:O95302