GDF11 - Growth/differentiation factor 11 - human protein (Function)
 
Home Recent activites arrow-down favorite My favorites arrow-down favorite My labels arrow-down Downloads
Back to ...  
Publication View
Protein
Gene
References

 
GDF11 »  Growth/differentiation factor 11  (GDF-11)
 
Protein also known as:  Bone morphogenetic protein 11 (BMP-11).
Gene name:  GDF11
Family name: TGF-beta
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 17 1
GENE REF ISO

Function

 show evidences
Overview 
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.  
  • CuratedUniProtKB
GO molecular function 
Cytokine activitydefinition[GO:0005125]  
  • IEAUniProtKB KW
Growth factor activitydefinition[GO:0008083]  
  • IEAUniProtKB KW
GO biological process 
Camera-type eye morphogenesisdefinition[GO:0048593] silver  
  • IEAOrtholog Compara
Cell maturationdefinition[GO:0048469] silver  
  • IEAOrtholog Compara
Growthdefinition[GO:0040007] silver  
  • IEAInterPro 2 GO
Mesoderm developmentdefinition[GO:0007498]  
1
  • TASUniProtKB
Metanephros developmentdefinition[GO:0001656] silver  
  • IEAOrtholog Compara
Negative regulation of cell differentiationdefinition[GO:0045596] silver  
  • IEAOrtholog Compara
Negative regulation of cell proliferationdefinition[GO:0008285] silver  
  • IEAOrtholog Compara
Nervous system developmentdefinition[GO:0007399]  
1
  • TASUniProtKB
Pancreas developmentdefinition[GO:0031016] silver  
  • IEAOrtholog Compara
Skeletal system developmentdefinition[GO:0001501]  
1
  • TASUniProtKB
Spinal cord anterior/posterior patterningdefinition[GO:0021512] silver  
  • IEAOrtholog Compara
Ureteric bud developmentdefinition[GO:0001657] silver  
  • IEAOrtholog Compara
 

Keywords

Molecular function 
Cytokine  definition   [KW-0202]
Growth factor  definition   [KW-0339]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: GDF11
GenomeRNAi: 10220
PRO: PR:O95390