TGDS - dTDP-D-glucose 4,6-dehydratase - human protein (Function)
 
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Protein
Gene
References

 
TGDS »  dTDP-D-glucose 4,6-dehydratase   [ EC 4.2.1.46 ]
 
Gene name:  TGDS
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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GO molecular function 
Coenzyme bindingdefinition[GO:0050662] silver  
  • IEAInterPro 2 GO
dTDP-glucose 4,6-dehydratase activitydefinition[GO:0008460]  
  • IEAEC 2 GO
GO biological process 
Nucleotide-sugar metabolic processdefinition[GO:0009225] silver  
  • IEAInterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 4.2.1.46: dTDP-alpha-D-glucose dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O.  
  • CuratedUniProtKB
It requires the following cofactor
NAD (By similarity).  
  • CuratedUniProtKB
Pathways 
According to KEGG, this protein belongs to the following pathway:
Metabolic pathways  hsa01100+23483  
 

Keywords

Molecular function 
Lyase  definition   [KW-0456]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GenomeRNAi: 23483
PRO: PR:O95455