LARGE - Glycosyltransferase-like protein LARGE1 - human protein (Function)
 
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Protein
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References

 
LARGE »  Glycosyltransferase-like protein LARGE1   [ EC 2.4.-.- ]
 
Protein also known as:  Acetylglucosaminyltransferase-like 1A.
Gene name:  LARGE
Family name: Glycosyltransferase 8
Entry whose protein(s) existence is based on evidence at protein level
extend overview
1 39 2
GENE REF ISO

Function

 show evidences
Overview 
Glycosyltransferase which participates in glycosylation of alpha-dystroglycan. May carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. May be involved in the addition of a repeated disaccharide unit.  
2
  • CuratedUniProtKB
GO molecular function 
Acetylglucosaminyltransferase activitydefinition[GO:0008375]  
1
  • TASPINC
Transferase activity, transferring glycosyl groupsdefinition[GO:0016757]  
1
  • TASUniProtKB
GO biological process 
Glycoprotein biosynthetic processdefinition[GO:0009101]  
1
  • TASUniProtKB
Glycosphingolipid biosynthetic processdefinition[GO:0006688]  
1
  • TASUniProtKB
Muscle cell cellular homeostasisdefinition[GO:0046716]  
  • ISSOrtholog Curator
N-acetylglucosamine metabolic processdefinition[GO:0006044]  
1
  • TASPINC
Protein glycosylationdefinition[GO:0006486]  
  • IEAUniPathway
Enzymatic activity 
According to CAZy, this protein is belongs to the following pathways:
Glycosyltransferase Family 49  GT49  
Glycosyltransferase Family 8  GT8  
Pathways 
This protein is involved in the following pathway
 

Keywords

Molecular function 
Glycosyltransferase  definition   [KW-0328]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: LARGE
GenomeRNAi: 9215
PRO: PR:O95461