CDS2 - Phosphatidate cytidylyltransferase 2 - human protein (Function)
 
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Protein
Gene
References

 
CDS2 »  Phosphatidate cytidylyltransferase 2
 
Gene name:  CDS2
Family name: CDS
Entry whose protein(s) existence is based on evidence at protein level
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GENE REF ISO

Function

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Overview 
Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.  
  • CuratedUniProtKB
GO molecular function 
Phosphatidate cytidylyltransferase activitydefinition[GO:0004605]  
1
  • NASUniProtKB
GO biological process 
CDP-diacylglycerol biosynthetic processdefinition[GO:0016024]  
  • IEAUniPathway
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.7.41: CTP + phosphatidate diphosphate + CDP-diacylglycerol.  
  • CuratedUniProtKB
Pathways 
This protein is involved in the following pathway
According to KEGG, this protein belongs to the following pathways:
Glycerophospholipid metabolism  hsa00564+8760  
Metabolic pathways  hsa01100+8760  
Phosphatidylinositol signaling system  hsa04070+8760  
According to Reactome, this protein belongs to the following pathway:
Synthesis of PG  REACT_121280  
 

Keywords

Biological process 
Lipid biosynthesis  definition   [KW-0444]
Lipid metabolism  definition   [KW-0443]
Phospholipid biosynthesis  definition   [KW-0594]
Phospholipid metabolism  definition   [KW-1208]
Molecular function 
Nucleotidyltransferase  definition   [KW-0548]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

GeneWiki: CDS2
GenomeRNAi: 8760
PRO: PR:O95674