OXSR1 - Serine/threonine-protein kinase OSR1 - human protein (Function)
 
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OXSR1 »  Serine/threonine-protein kinase OSR1   [ EC 2.7.11.1 ]
 
Protein also known as:  Oxidative stress-responsive 1 protein.
Gene name:  OXSR1
Entry whose protein(s) existence is based on evidence at protein level
extend overview
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GENE REF ISO

Function

 show evidences
Overview 
Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.  
3
  • UniProtKB
GO molecular function 
ATP bindingdefinition[GO:0005524]  
1
  • UniProtKB
Magnesium ion bindingdefinition[GO:0000287]  
1
  • UniProtKB
Protein bindingdefinition[GO:0005515]  
4
  • IntAct
  • ParkinsonsUK-UCL
Protein serine/threonine kinase activitydefinition[GO:0004674]  
2
  • ParkinsonsUK-UCL
  • UniProtKB
Receptor signaling protein serine/threonine kinase activitydefinition[GO:0004702]  
1
  • RefGenome
GO biological process 
Cellular hypotonic responsedefinition[GO:0071476] silver  
1
  • Ortholog Compara
Intracellular signal transductiondefinition[GO:0035556]  
1
  • UniProtKB
Negative regulation of potassium ion transmembrane transporter activitydefinition[GO:1901017] silver  
1
  • Ortholog Compara
Negative regulation of rubidium ion transmembrane transporter activitydefinition[GO:2000687] silver  
1
  • Ortholog Compara
Peptidyl-threonine phosphorylationdefinition[GO:0018107]  
1
  • ParkinsonsUK-UCL
Protein phosphorylationdefinition[GO:0006468]  
1
  • UniProtKB
Response to oxidative stressdefinition[GO:0006979] silver  
1
  • Ortholog Compara
Signal transduction by protein phosphorylationdefinition[GO:0023014]  
2
  • RefGenome
  • InterPro 2 GO
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.11.1: ATP + a protein ADP + a phosphoprotein.  
2
  • UniProtKB
It requires the following cofactor
 Mg(2+)  
2
  • UniProtKB
It is regulated in the following manner
By autophosphorylation on threonine.  
2
  • UniProtKB
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Serine/threonine-protein kinase  definition   [KW-0723]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]
 

Further external links

Other
GeneWiki: OXSR1
GenomeRNAi: 9943
PRO: PR:O95747
Chemistry
GuidetoPHARMACOLOGY: 2132