AK1 - Adenylate kinase isoenzyme 1 - human protein (Function)
 
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Protein
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References

 
AK1 »  Adenylate kinase isoenzyme 1  (AK 1)
 
Protein also known as:  ATP-AMP transphosphorylase 1.
Gene name:  AK1
Family name: Adenylate kinase
This protein has been shown to exist at protein level
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GENE REF ISO

Function

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Overview 
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.  
  • CuratedUniProtKB
GO molecular function 
Adenylate kinase activitydefinition[GO:0004017]  
  • IEAEC 2 GO
ATP bindingdefinition[GO:0005524]  
  • IEAUniProtKB KW
GO biological process 
ATP metabolic processdefinition[GO:0046034] silver  
  • IEAInterPro 2 GO
Cell cycle arrestdefinition[GO:0007050] silver  
  • IEAOrtholog Compara
Enzymatic activity 
This protein acts as an enzyme. It is known to catalyze the following reaction
EC 2.7.4.3: ATP + AMP 2 ADP.  
  • CuratedUniProtKB
 
More information is available from:
Pathways 
According to KEGG, this protein belongs to the following pathways:
Metabolic pathways  hsa01100+203  
Purine metabolism  hsa00230+203  
According to Reactome, this protein belongs to the following pathway:
Metabolism  REACT_111217  
 

Keywords

Molecular function 
Kinase  definition   [KW-0418]
Transferase  definition   [KW-0808]
Technical term 
Reference proteome  definition   [KW-1185]